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Article

The flavonoid rutin modulates microglial/macrophage activation to a CD150/CD206 M2 phenotype.

Chemico-biological interactions - 25 Aug 2017

Bispo da Silva Alessandra, Cerqueira Coelho Paulo Lucas, Alves Oliveira Amparo Jessika, Alves de Almeida Carneiro Monique Marylin, Pereira Borges Julita Maria, Dos Santos Souza Cleide, Dias Costa Maria de Fátima, Mecha Miriam, Guaza Rodriguez Carmen, Amaral da Silva Victor Diogenes, Lima Costa Silvia

Abstract excerpt

Rutin is a glycosylated flavonoid present in many fruits and plants that has been demonstrated to have anti-inflammatory and antioxidant properties. However, little is known about the mechanisms underlying microglial activation and its effects on the regulation of cytokines and chemokines associated with inflammatory responses in the central nervous system. In this study we examined the effect of rutin on resting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28693884
DOI: 10.1016/j.cbi.2017.07.004

Genes

TNF
PTGS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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