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Article

Failure to Identify Somatic Mutations in Monozygotic Twins Discordant for Schizophrenia by Whole Exome Sequencing.

Chinese medical journal - 20 Mar 2016

Lyu Nan, Guan Li-Li, Ma Hong, Wang Xi-Jin, Wu Bao-Ming, Shang Fan-Hong, Wang Dan, Wen Hong, Yu Xin

Abstract excerpt

BACKGROUND: Schizophrenia (SCZ) is a severe, debilitating, and complex psychiatric disorder with multiple causative factors. An increasing number of studies have determined that rare variations play an important role in its etiology. A somatic mutation is a rare form of genetic variation that occurs at an early stage of embryonic development and is thought to contribute substantially to the development of SCZ....

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Identifiers

PMID: 26960372
DOI: 10.4103/0366-6999.178009
PMCID: PMC4804415

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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