Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole genome sequencing study of identical twins discordant for psychosis.

Translational psychiatry - 30 Jul 2024

Ormond Cathal, Ryan Niamh M, Hedman Anna M, Cannon Tyrone D, Sullivan Patrick F, Gill Michael, Hultman Christina, Heron Elizabeth A, Johansson Viktoria, Corvin Aiden

Abstract excerpt

Monozygotic (MZ) twins are often thought to have identical genomes, but recent work has shown that early post-zygotic events can result in a spectrum of DNA variants that are different between MZ twins. Such variants may explain phenotypic discordance and contribute to disease etiology. Here we performed whole genome sequencing in 17 pairs of MZ twins discordant for a psychotic disorder (schizophrenia,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Diseases in Twins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Forkhead Transcription Factors

Share to Psychotic Disorders

Share to Schizophrenia

Share to Twins, Monozygotic

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 39080272
DOI: 10.1038/s41398-024-02982-0
PMCID: PMC11289105

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole genome sequencing study of identical twins discordant for psychosis.PMID 39080272Read ↗

Whole-genome sequencing of monozygotic twins discordant for schizophrenia indicates multiple genetic risk factors for schizophrenia.Semantic proximity Read ↗

Whole-exome sequencing in a family with a monozygotic twin pair concordant for schizophrenia and a follow-up case-control study of identified de-novo variants.Semantic proximity Read ↗

Failure to Identify Somatic Mutations in Monozygotic Twins Discordant for Schizophrenia by Whole Exome Sequencing.Semantic proximity Read ↗

VarScan2 analysis of de novo variants in monozygotic twins discordant for schizophrenia.Semantic proximity Read ↗

A pilot study on commonality and specificity of copy number variants in schizophrenia and bipolar disorder.Semantic proximity Read ↗

Association analysis of FEZ1 variants with schizophrenia in Japanese cohorts.Semantic proximity Read ↗

Whole-exome sequencing in a family with a monozygotic twin pair concordant for autism spectrum disorder and a follow-up study.Semantic proximity Read ↗

Copy number variants in siblings of Mexican origin concordant for schizophrenia or bipolar disorder.Semantic proximity Read ↗

Genome sequencing broadens the range of contributing variants with clinical implications in schizophrenia.Semantic proximity Read ↗

Multiplex Portuguese Families as a Lens into rare mutations and the Shared Genetic Architecture of Schizophrenia, Mood Disorders, and Autism Spectrum DisordersSemantic proximity Read ↗

De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability.Semantic proximity Read ↗

The benefit of diagnostic whole genome sequencing in schizophrenia and other psychotic disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.