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Article

TERT promoter mutated WHO grades II and III gliomas are located preferentially in the frontal lobe and avoid the midline.

International journal of clinical and experimental pathology - 1 Jan 2015

Sun Ze-Lin, Chan Aden Ka-Yin, Chen Ling-Chao, Tang Chao, Zhang Zhen-Yu, Ding Xiao-Jie, Wang Yang, Sun Chong-Ran, Ng Ho-Keung, Yao Yu, Zhou Liang-Fu

Abstract excerpt

The promoter region of telomerase reverse transcriptase (TERTp) and isocitrate dehydrogenase (IDH) have been regarded as biomarkers with distinct clinical and phenotypic features. Investigated the possible correlations between tumor location and genetic alterations would enhance our understanding of gliomagenesis and heterogeneity of glioma. We examined mutations of TERTp and IDH by direct sequencing and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to In Situ Hybridization, Fluorescence

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Source

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Identifiers

PMID: 26617880
PMCID: PMC4637696

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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TERT promoter mutated WHO grades II and III gliomas are located preferentially in the frontal lobe and avoid the midline.PMID 26617880Read ↗

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