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Article

Interleukin-1β mediates high glucose induced phenotypic transition in human aortic endothelial cells.

Cardiovascular diabetology - 5 Mar 2016

Zhu Dong-Dong, Tang Ri-Ning, Lv Lin-Li, Wen Yi, Liu Hong, Zhang Xiao-Liang, Ma Kun-Ling, Liu Bi-Cheng

Abstract excerpt

BACKGROUND: Previous studies have shown that high glucose (HG) induced endothelial cell (EC) damage via a phenotypic transition of EC. There is increasing evidence suggesting the role of inflammatory cytokines in mediated HG-induced EC damage. However, little is known about the potential role of interleukin-1β (IL-1β) in the process. The aim of present study was to investigate whether IL-1β mediated HG-induced...

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Identifiers

PMID: 26944557
DOI: 10.1186/s12933-016-0358-9
PMCID: PMC4779230

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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