Article

Dapagliflozin restores diabetes-associated decline in vasculogenic capacity of endothelial progenitor cells via activating AMPK-mediated inhibition of inflammation and oxidative stress

2022-11-01

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Sodium-glucose cotransporter 2 inhibitors (SGLT2i) provide added vascular protection beyond glucose lowering to patients with type 2 diabetes mellitus (T2DM). Endothelial progenitor cells (EPCs) are an important endogenous repair mechanism for diabetic vascular complications. Yet, whether SGLT2i protect vessels in diabetic patients by improving the function o...

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Literature Corpus work: dea277fe-9444-5809-b8dc-b10de414c187
DOI: 10.21203/rs.3.rs-694662/v2

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