Article
[The effects and mechanisms of high glucose on the phenotype transformation of rat vascular smooth muscle cells].
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology - 1 Sept 2015
Zhang Jing, Chu Hai-rong, Guo Ying, Liu Jian-hua, Li Wen-Ping, Li Hong, Cheng Min
Abstract excerpt
OBJECTIVE: To investigate the effects and mechanisms of high glucose on the phenotype transformation of rat vascular smooth muscle cells (VSMCs). METHODS: VSMCs ere isolated from rat thoracic aorta and the 3rd-5th VSMCs were incubated with normal glucose (5.5 mmol/L), high glucose (25 mmol/L), or high glucose (25 mmol/L) + P38 inhibitor (25 mmol/L +SB203580) for another 24 hours. Then the gene expression of...
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