Article
A Dot/Icm-translocated ankyrin protein of Legionella pneumophila is required for intracellular proliferation within human macrophages and protozoa.
Molecular microbiology - 1 Nov 2008
Al-Khodor Souhaila, Price Christopher T, Habyarimana Fabien, Kalia Awdhesh, Abu Kwaik Yousef
Abstract excerpt
The Dot/Icm type IV secretion system of Legionella pneumophila translocates numerous bacterial effectors into the host cell and is essential for bacterial proliferation within macrophages and protozoa. We have recently shown that L. pneumophila strain AA100/130b harbours 11 genes encoding eukaryotic-like ankyrin (Ank) proteins, a family of proteins involved in various essential eukaryotic cellular processes. In...
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