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Article

Complex Interplay of the UL136 Isoforms Balances Cytomegalovirus Replication and Latency

1 Mar 2016

Abstract excerpt

UNLABELLED: Human cytomegalovirus (HCMV), a betaherpesvirus, persists indefinitely in the human host through poorly understood mechanisms. The UL136 gene is carried within a genetic locus important to HCMV latency termed the UL133/8 locus, which also carries UL133, UL135, and UL138. Previously, we demonstrated that UL136 is expressed as five protein isoforms ranging from 33-kDa to 19-kDa, arising from alternative...

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PMID: 26933055
DOI: 10.1128/mbio.01986-15

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