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Human Cytomegalovirus <i>UL135</i> and <i>UL136</i> Genes Are Required for Postentry Tropism in Endothelial Cells

16 Apr 2015

Abstract excerpt

UNLABELLED: Endothelial cells (ECs) are a critical target of viruses, and infection of the endothelium represents a defining point in viral pathogenesis. Human cytomegalovirus (HCMV), the prototypical betaherpesvirus, encodes proteins specialized for entry into ECs and delivery of the genome to the nuclei of ECs. Virus strains competent to enter ECs replicate with differing efficiencies, suggesting that the virus...

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PMID: 25878111
DOI: 10.1128/jvi.00284-15

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Human Cytomegalovirus <i>UL135</i> and <i>UL136</i> Genes Are Required for Postentry Tropism in Endothelial CellsPMID 25878111Read ↗

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