Article
[Single nucleotide polymorphisms in cell cycle regulator p21 and p27 genes are associated with susceptibility to epithelial ovarian cancer].
Zhonghua fu chan ke za zhi - 1 Mar 2008
Jin Xia, Kang Shan, Wang Na, Xing Yan-Ping, Li Yan
Abstract excerpt
OBJECTIVE: To investigate the association of single nucleotide polymorphisms (SNP) in p21 and p27 genes with the risk of epithelial ovarian cancer (EOC). METHODS: Genotypes were analyzed by polymerase chain reaction-restrictive fragment length polymorphism (PCR-RFLP) method in 234 patients with EOC and 284 control women in China. RESULTS: (1) The frequencies of the p21 in healthy controls were 34.2%, 49.6% and...
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