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Identification of Potential Therapeutic Targets and Molecular Regulatory Mechanisms for Osteoporosis by Bioinformatics Methods

1 Jan 2021

Abstract excerpt

BACKGROUND: Osteoporosis is characterized by low bone mass, deterioration of bone tissue structure, and susceptibility to fracture. New and more suitable therapeutic targets need to be discovered. METHODS: We collected osteoporosis-related datasets (GSE56815, GSE99624, and GSE63446). The methylation markers were obtained by differential analysis. Degree, DMNC, MCC, and MNC plug-ins were used to screen the...

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Bone Metabolism and Diseases
Ferroptosis and cancer prognosis
MicroRNA in disease regulation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33778083
DOI: 10.1155/2021/8851421

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