Article
Association between DNA repair gene ATM polymorphisms and oral cancer susceptibility.
The Laryngoscope - 1 Dec 2010
Bau Da-Tian, Chang Chao-Hsiang, Tsai Ming-Hsui, Chiu Chang-Fang, Tsou Yung-An, Wang Rou-Fen, Tsai Chia-Wen, Tsai Ru-Yin
Abstract excerpt
OBJECTIVES/HYPOTHESIS: The ataxia-telangiectasia mutated (ATM) is thought to play a major role in the caretaking of the overall genome stability, and its mutations have been implicated in human cancers. However, the role of ATM polymorphisms in oral carcinogenesis is largely unexplored. Thus, the polymorphic variants of ATM were first investigated for their association with oral cancer susceptibility. STUDY...
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