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Article

Association of XRCC1 gene polymorphisms with chronic myeloid leukemia in the population of Andhra Pradesh, India.

Hematology (Amsterdam, Netherlands) - 1 May 2013

Annamaneni Sandhya, Gorre Manjula, Kagita Sailaja, Addepalli Kasyap, Digumarti Raghunadha Rao, Satti Vishnupriya, Battini Mohan Reddy

Abstract excerpt

Chronic myeloid leukemia (CML), a clonal myeloproliferative disorder, is characterized primarily by the presence of chimeric BCR-ABL oncogene, and its progression from chronic to blast phase is associated with the accumulation of additional molecular and chromosomal abnormalities. The molecular mechanisms underlying this genetic instability are poorly understood. The activity of BCR-ABL is known to be associated...

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Source

Identifiers

PMID: 23320983
DOI: 10.1179/1607845412Y.0000000040

Genes

XRCC1
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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