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Article

The interaction of combined effects of the BDNF and PRKCG genes and negative life events in major depressive disorder.

Psychiatry research - 30 Mar 2016

Yang Chunxia, Sun Ning, Liu Zhifen, Li Xinrong, Xu Yong, Zhang Kerang

Abstract excerpt

Major depressive disorder (MDD) is a mental disorder that results from complex interplay between multiple and partially overlapping sets of susceptibility genes and environmental factors. The brain derived neurotrophic factor (BDNF) and Protein kinase C gamma type (PRKCG) are logical candidate genes in MDD. Among diverse environmental factors, negative life events have been suggested to exert a crucial impact on...

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Source

Identifiers

PMID: 26921055
DOI: 10.1016/j.psychres.2016.01.076

Genes

BDNF
PRKCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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