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Article

The interaction of miR-34b/c polymorphisms and negative life events increases susceptibility to major depressive disorder in Han Chinese population.

Neuroscience letters - 9 Jun 2017

Xu Cheng, Yang Chunxia, Zhang Aixia, Xu Yong, Li Xinrong, Liu Zhifen, Liu Sha, Sun Ning, Zhang Kerang

Abstract excerpt

BACKGROUND: Previous studies have shown that microRNAs(miRNAs) are involved in the pathogenesis of MDD; in particular, miR-34b/c has been implicated in MDD risk and found to exert antidepressant effects. However, the effects of miR-34b/c polymorphisms on MDD risk have not been investigated. METHODS: In this study, we evaluated the effect of miR-34b/c gene polymorphisms and their interaction with negative life...

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Identifiers

PMID: 28461137
DOI: 10.1016/j.neulet.2017.04.061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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