Article
Complex approaches to study complex trait genetics in multiple sclerosis.
Ideggyogyaszati szemle - 30 Sept 2014
Kálmán Bernadette
Abstract excerpt
Multiple sclerosis (MS) is a complex trait disorder defined by several genes and their interactions with environmental factors. A comprehensive exploration of the susceptibility variants had not been feasible until recently when new developments in biotechnology and bioinformatics made possible sequencing of the whole human genome, cataloguing of nucleotide variants and alignments of these variants in haplotypes....
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