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Article

Falls, fracture and frailty risk in multiple sclerosis: a Mendelian Randomization study to identify shared genetics.

Journal of bone and mineral metabolism - 1 May 2024

Jeong Sohyun, Tsai Ming-Ju, Shen Changbing, Hsu Yi-Hsiang

Abstract excerpt

INTRODUCTION: Patients with multiple sclerosis (MS) commonly present musculoskeletal disorders characterized by lower bone mineral density (BMD) and muscle weakness. However, the underlying etiology remains unclear. Our objective is to identify shared pleiotropic genetic effects and estimate the causal relationship between MS and musculoskeletal disorders. MATERIALS AND METHODS: We conducted linkage...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38801451
DOI: 10.1007/s00774-024-01504-8
PMCID: PMC11147890

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