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Article

Methionine synthase A2756G variation is associated with the risk of retinoblastoma in Iranian children.

Cancer epidemiology - 1 Dec 2015

Akbari Mohammad Taghi, Naderi Asieh, Saremi Leila, Sayad Arezou, Irani Shiva, Ahani Ali

Abstract excerpt

Association of epigenetic modifications with cancer has been widely studied. Gene-specific hypermethylation and global DNA hypomethylation are the most frequently observed patterns in great number of tumors. The methionine synthase (MTR) gene plays key role in maintaining adequate intracellular folate, methionine and normal homocysteine concentrations and, its polymorphism have been associated with the risk of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26595280
DOI: 10.1016/j.canep.2015.11.002

Genes

MTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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