Article
[Large Granular Lymphocytic Leukemia and JAK/STAT Signaling Pathway--Review].
Zhongguo shi yan xue ye xue za zhi - 1 Feb 2016
Qiu Zhi-Yuan, Fan Yu
Abstract excerpt
Large granular lymphocytic leukemia (LGLL) is a rare lymphoproliferative disorder of clonal expansion of cytotoxic T- or NK-cells in blood and bone marrow, and often associated with autoimmune disorders. According to the current WHO classification of the hematopoietic and lymphoid tissue tumors, the clonal LGL expansions are further classified as T-cell large granular lymphocytic leukemia (T-LGLL), chronic...
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