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T-cell and natural killer-cell large granular lymphocyte leukemia neoplasias

13 Jul 2011

Abstract excerpt

Large granular lymphocyte (LGL) leukemia is a rare disorder of cytotoxic lymphocytes. LGL cells play an integral role in the immune system and are divided into two major lineages of CD3(-)natural killer (NK) cells and CD3(+) T cells that circulate throughout the blood in search of infected cells, in which they will make contact through a receptor ligand and induce cell death. LGL cells are also programmed to...

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PMID: 21749307
DOI: 10.3109/10428194.2011.593276

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