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Article

Large granular lymphocyte leukemia: a clonal disorder with autoimmune manifestations.

Hematology. American Society of Hematology. Education Program - 6 Dec 2024

Marchand Tony, Pastoret Cédric, Moignet Aline, Roussel Mikael, Lamy Thierry

Abstract excerpt

Large granular lymphocyte (LGL) leukemia is a rare lymphoproliferative disorder characterized by an expansion of clonal T or natural killer lymphocytes. Neutropenia-related infections and anemia represent the main manifestations. LGL leukemia is frequently associated with autoimmune disorders such as rheumatoid arthritis, Sjögren's syndrome, autoimmune endocrinopathies, vasculitis, or autoimmune cytopenia. Recent...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39644019
DOI: 10.1182/hematology.2024000539
PMCID: PMC11665628

Genes

STAT3

Provenance

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