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Article

A modern view of LGL leukemia.

Blood - 31 Oct 2024

Marchand Tony, Lamy Thierry, Loughran Thomas P

Abstract excerpt

ABSTRACT: Large granular lymphocytic leukemia (LGLL) is a rare lymphoproliferative chronic disorder characterized by expansion of either T or natural killer (NK) cytotoxic cells. In contrast to Epstein-Barr virus-induced aggressive NK-LGLL, chronic T-LGLL and NK-LGLL are indolent diseases affecting older patients with a median age of 66.5 years. LGLL is frequently associated with autoimmune disorders, most...

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Identifiers

PMID: 38848524
DOI: 10.1182/blood.2023021790

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