Article
LGL leukemia and autoimmunity - the borderline between autoimmune disease and cancer is becoming blurred.
Duodecim; laaketieteellinen aikakauskirja - 1 Jan 2000
Savola Paula, Rajala Hanna, Mustjoki Satu
Abstract excerpt
Large granular lymphocyte (LGL) leukemia is a chronic hematological disease, in which the diseased cells consist of clonal large, mature T or NK cells. Major symptoms and findings of the disease include anemia, neutropenia and rheumatoid arthritis. Immunosuppressive treatments, such as methotrexate, usually relieve the symptoms in patients. In LGL leukemia, next-generation sequencing has recently revealed...
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