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Clinical Manifestations and Genetic Profile of Chinese Patients with NK-Cell Large Granular Lymphocytic Leukemia-A Single-Center Retrospective Analysis.

International journal of molecular sciences - 13 Jul 2026

Zhuang Zhe, Zhu Huiying, Chen Chao, Di Yiao, He Zhangyuting, Zhang Wei, Zhou Daobin, Zhang Yan

Abstract excerpt

Natural killer cell large granular lymphocytic leukemia (NK-LGLL) is a rare and heterogenous lymphoproliferative disorder. This study retrospectively evaluated 35 consecutive Chinese patients (median age 58 years) to evaluate their unique clinical-biological profiles and treatment responses. Our Chinese population exhibited a distinct comorbidity spectrum, characterized by a lower prevalence of concurrent...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42511571
DOI: 10.3390/ijms27146227
PMCID: PMC13410105

Genes

STAT3

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