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Article

Natural Single-Nucleotide Variations in the HIV-1 Genomic SA1prox Region Can Alter Viral Replication Ability by Regulating Vif Expression Levels.

Journal of virology - 1 May 2016

Nomaguchi Masako, Doi Naoya, Sakai Yosuke, Ode Hirotaka, Iwatani Yasumasa, Ueno Takamasa, Matsumoto Yui, Miyazaki Yasuyuki, Masuda Takao, Adachi Akio

Abstract excerpt

UNLABELLED: We previously found that natural single-nucleotide variations located within a proximal region of splicing acceptor 1 (SA1prox) in the HIV-1 genome could alter the viral replication potential and mRNA expression pattern, especially the vif mRNA level. Here, we studied the virological and molecular basis of nucleotide sequence variations in SA1prox for alterations of viral replication ability....

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Source

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Identifiers

PMID: 26912631
DOI: 10.1128/JVI.02939-15
PMCID: PMC4836328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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