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Article

Alternative splicing: regulation of HIV‐1 multiplication as a target for therapeutic action

15 Jan 2010

Abstract excerpt

The retroviral life cycle requires that significant amounts of RNA remain unspliced and perform several functions in the cytoplasm. Thus, the full-length RNA serves both the viral genetic material that will be encapsulated in viral particles and the mRNA encoding structural and enzymatic proteins required for viral replication. Simple retroviruses produce one single-spliced env RNA from the full-length precursor...

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Identifiers

PMID: 20082634
DOI: 10.1111/j.1742-4658.2009.07522.x

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