Article
Role of Toll-like receptor 2 in innate resistance to Group B Streptococcus.
Microbial pathogenesis - 1 Jan 2008
Asplin Iain R, Carl David J, Way Sing Sing, Jones Amanda L
Abstract excerpt
The Gram-positive bacterium Group B Streptococcus (GBS) is an important cause of serious neonatal and adult infections. Toll-like receptor 2 (TLR2) recognizes components of the cell wall of Gram-positive bacteria and is critical for defense against certain invasive pathogens. In GBS, penicillin-binding protein 1a (PBP1a), encoded by ponA, is required for virulence. PBPs participate in cell wall synthesis and in...
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