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Article

Lipoglycans contribute to innate immune detection of mycobacteria.

PloS one - 1 Jan 2011

Krishna Shyam, Ray Aurélie, Dubey Shiv K, Larrouy-Maumus Gérald, Chalut Christian, Castanier Romain, Noguera Audrey, Gilleron Martine, Puzo Germain, Vercellone Alain, Nampoothiri K Madhavan, Nigou Jérôme

Abstract excerpt

Innate immune recognition is based on the detection, by pattern recognition receptors (PRRs), of molecular structures that are unique to microorganisms. Lipoglycans are macromolecules specific to the cell envelope of mycobacteria and related genera. They have been described to be ligands, as purified molecules, of several PRRs, including the C-type lectins Mannose Receptor and DC-SIGN, as well as TLR2. However,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22164297
DOI: 10.1371/journal.pone.0028476
PMCID: PMC3229593

Genes

TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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