Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14,463 cases and 44,188 controls.

doi:10.1093/carcin/bgw014

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Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14,463 cases and 44,188 controls.

Carcinogenesis - 1 Mar 2016

Kang Xiaozheng, Liu Hongliang, Onaitis Mark W, Liu Zhensheng, Owzar Kouros, Han Younghun, Su Li, Wei Yongyue, Hung Rayjean J, Brhane Yonathan, McLaughlin John, Brennan Paul, Bickeböller Heike, Rosenberger Albert, Houlston Richard S, Caporaso Neil, Landi Maria Teresa, Heinrich Joachim, Risch Angela, Wu Xifeng, Ye Yuanqing, Christiani David C, Amos Christopher I, Wei Qingyi

Abstract excerpt

Centrosome abnormalities are often observed in premalignant lesions and in situ tumors and have been associated with aneuploidy and tumor development. We investigated the associations of 9354 single-nucleotide polymorphisms (SNPs) in 106 centrosomal genes with lung cancer risk by first using the summary data from six published genome-wide association studies (GWASs) of the Transdisciplinary Research in Cancer of...

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PMID: 26905588
DOI: 10.1093/carcin/bgw014
PMCID: PMC4804128

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BRCA2
TUBB

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