Article
Combined analysis with copy number variation identifies risk loci in lung cancer.
BioMed research international - 1 Jan 2014
Li Xinlei, Chen Xianfeng, Hu Guohong, Liu Yang, Zhang Zhenguo, Wang Ping, Zhou You, Yi Xianfu, Zhang Jie, Zhu Yufei, Wei Zejun, Yuan Fei, Zhao Guoping, Zhu Jun, Hu Landian, Kong Xiangyin
Abstract excerpt
BACKGROUND: Lung cancer is the most important cause of cancer mortality worldwide, but the underlying mechanisms of this disease are not fully understood. Copy number variations (CNVs) are promising genetic variations to study because of their potential effects on cancer. METHODOLOGY/PRINCIPAL FINDINGS: Here we conducted a pilot study in which we systematically analyzed the association of CNVs in two lung cancer...
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