Article
Significant association of serum uric acid levels with SLC2A9 rs11722228 among a Japanese population.
Molecular genetics and metabolism - 1 Aug 2011
Hamajima Nobuyuki, Okada Rieko, Kawai Sayo, Hishida Asahi, Morita Emi, Yin Guang, Wakai Kenji, Matsuo Hirotaka, Inoue Hiroki, Takada Yuzo, Asai Yatami, Mori Atsuyoshi, Naito Mariko
Abstract excerpt
Genome-wide association studies identified that SLC2A9 (GLUT9) gene polymorphisms were associated with serum uric acid (SUA) levels. Among the Japanese, a C/T polymorphism in intron 8 (rs11722228) was reported to be highly significant, though the function and strength of association were unknown. This study aimed to confirm the association, estimating the means of SUA according to the genotype, as well as OR of...
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