Article
Common variants related to serum uric acid concentrations are associated with glucose metabolism and insulin secretion in a Chinese population.
PloS one - 1 Jan 2015
Sun Xue, Zhang Rong, Jiang Feng, Tang Shanshan, Chen Miao, Peng Danfeng, Yan Jing, Wang Tao, Wang Shiyun, Bao Yuqian, Hu Cheng, Jia Weiping
Abstract excerpt
BACKGROUND: Elevated serum uric acid concentration is an independent risk factor and predictor of type 2 diabetes (T2D). Whether the uric acid-associated genes have an impact on T2D remains unclear. We aimed to investigate the effects of the uric acid-associated genes on the risk of T2D as well as glucose metabolism and insulin secretion. METHOD: We recruited 2,199 normal glucose tolerance subjects from the...
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