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Article

Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals.

Scientific reports - 8 Jun 2020

Cho Sung Kweon, Kim Beomsu, Myung Woojae, Chang Yoosoo, Ryu Seungho, Kim Han-Na, Kim Hyung-Lae, Kuo Po-Hsiu, Winkler Cheryl A, Won Hong-Hee

Abstract excerpt

Increased serum uric acid (SUA) levels cause gout and are associated with multiple diseases, including chronic kidney disease. Previous genome-wide association studies (GWAS) have identified more than 180 loci that contribute to SUA levels. Here, we investigated genetic determinants of SUA level in the Korean population. We conducted a GWAS for SUA in 6,881 Korean individuals, calculated polygenic risk scores...

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Identifiers

PMID: 32514006
DOI: 10.1038/s41598-020-66064-z
PMCID: PMC7280503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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