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Article

Effects of IL1B single nucleotide polymorphisms on depressive and anxiety symptoms are determined by severity and type of life stress.

Brain, behavior, and immunity - 1 Aug 2016

Kovacs David, Eszlari Nora, Petschner Peter, Pap Dorottya, Vas Szilvia, Kovacs Peter, Gonda Xenia, Juhasz Gabriella, Bagdy Gyorgy

Abstract excerpt

Interleukin-1β is one of the main mediators in the cross-talk between the immune system and the central nervous system. Higher interleukin-1β levels are found in mood spectrum disorders, and the stress-induced expression rate of the interleukin-1β gene (IL1B) is altered by polymorphisms in the region. Therefore we examined the effects of rs16944 and rs1143643 single nucleotide polymorphisms (SNPs) within the IL1B...

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Source

Identifiers

PMID: 26891860
DOI: 10.1016/j.bbi.2016.02.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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