Article
Cytokine Genes TNF, IL1A, IL1B, IL6, IL1RN and IL10, and childhood-onset mood disorders.
Neuropsychobiology - 1 Jan 2008
Misener V L, Gomez L, Wigg K G, Luca P, King N, Kiss E, Daróczi G, Kapornai K, Tamas Z, Mayer L, Gádoros J, Baji I, Kennedy J L, Kovacs M, Vetró A, Barr C L
Abstract excerpt
BACKGROUND/AIMS: Inflammatory cytokines induce a behavioral syndrome, known as sickness behavior, that strongly resembles symptoms typically seen in depression. This resemblance has led to the theory that an imbalance of inflammatory cytokine activity may be a contributing factor in depressive disorders. Support for this is found in multiple lines of evidence, such as the effects of cytokines on the activities of...
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