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Article

Mesenchymal Stem Cells Induce Suppressive Macrophages Through Phagocytosis in a Mouse Model of Asthma.

Stem cells (Dayton, Ohio) - 1 Jul 2016

Braza Faouzi, Dirou Stéphanie, Forest Virginie, Sauzeau Vincent, Hassoun Dorian, Chesné Julie, Cheminant-Muller Marie-Aude, Sagan Christine, Magnan Antoine, Lemarchand Patricia

Abstract excerpt

Mesenchymal stem cell (MSC) immunosuppressive functions make them attractive candidates for anti-inflammatory therapy in allergic asthma. However, the mechanisms by which they ensure therapeutic effects remain to be elucidated. In an acute mouse model of house dust mite (Der f)-induced asthma, one i.v. MSC injection was sufficient to normalize and stabilize lung function in Der f-sensitized mice as compared to...

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PMID: 26891455
DOI: 10.1002/stem.2344

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MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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