Article
Suppression of Canine Dendritic Cell Activation/Maturation and Inflammatory Cytokine Release by Mesenchymal Stem Cells Occurs Through Multiple Distinct Biochemical Pathways.
Stem cells and development - 15 Feb 2017
Wheat William H, Chow Lyndah, Kurihara Jade N, Regan Daniel P, Coy Jonathan W, Webb Tracy L, Dow Steven W
Abstract excerpt
Mesenchymal stem cells (MSC) represent a readily accessible source of cells with potent immune modulatory activity. MSC can suppress ongoing inflammatory responses by suppressing T cell function, while fewer studies have examined the impact of MSC on dendritic cell (DC) function. The dog spontaneous disease model represents an important animal model with which to evaluate the safety and effectiveness of cellular...
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