Article
Mesenchymal Stem Cells Direct the Immunological Fate of Macrophages.
Results and problems in cell differentiation - 1 Jan 2000
Luz-Crawford Patricia, Jorgensen Christian, Djouad Farida
Abstract excerpt
Mesenchymal stem cells (MSC) are multipotent stem cells with a broad well-described immunosuppressive potential. They are able to modulate both the innate and the adaptive immune response. Particularly, MSC are able to regulate the phenotype and function of macrophages that are critical for different biological processes including wound healing, inflammation, pathogenesis of several autoimmune diseases, and tumor...
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