Mutation in Rab11 results in abnormal organization of ommatidial cells and activation of JNK signaling in the Drosophila eye.

Abstract excerpt

Rab11(mo), a P insertion line of Rab11 showed degenerated ommatidia and excess cell death in larval/pupal eyes. Here, we demonstrate that Rab11 is essential for normal organization of ommatidial cells and their survival in Drosophila, and a mutation in this gene results in cytoskeleton disruption and activation of JNK signaling in the eye. The spatial organization of various cell types in compound eye, viz.,...

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