Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PIK3CA amplification is predictive of poor prognosis in Tunisian patients with nasopharyngeal carcinoma.

Cancer science - 1 Nov 2009

Fendri Ali, Khabir Abdelmajid, Mnejja Wafa, Sellami-Boudawara Tahia, Daoud Jamel, Frikha Mounir, Ghorbel Abdelmonem, Gargouri Ali, Mokdad-Gargouri Raja

Abstract excerpt

PI3Ks (phosphatidylinositol 3-kinases) are lipid kinases that regulate signalling pathways involved in cell proliferation, motility, and adhesion. Somatic mutations and amplification of the PIK3CA gene have been reported in various types of human cancers. However, little is known about the frequency and prognosis role of PIK3CA activation in nasopharyngeal carcinoma (NPC). This study was conducted with the aim to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Class I Phosphatidylinositol 3-Kinases

Share to Gene Amplification

Share to Nasopharyngeal Neoplasms

Share to Phosphatidylinositol 3-Kinases

Share to Polymorphism, Single-Stranded Conformational

Share to Prognosis

Source

Open in PubMed Open full text

Identifiers

PMID: 19735264
DOI: 10.1111/j.1349-7006.2009.01292.x
PMCID: PMC11158390

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PIK3CA amplification is predictive of poor prognosis in Tunisian patients with nasopharyngeal carcinoma.PMID 19735264Read ↗

Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas.Semantic proximity Read ↗

Analysis of PIK3CA and Akt/protein kinase B in head and neck squamous cell carcinoma.Semantic proximity Read ↗

Novel mutations of PIK3CA gene in head and neck squamous cell carcinoma.Semantic proximity Read ↗

<i>PIK3CA</i> mutations in nasopharyngeal carcinomaSemantic proximity Read ↗

<i>PIK3CA</i> mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinomaSemantic proximity Read ↗

PIK3CA mutation occurs in nasopharyngeal carcinoma but does not significantly influence the disease-specific survivalSemantic proximity Read ↗

PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches.Semantic proximity Read ↗

PIK3CA amplification is associated with poor prognosis among patients with curatively resected esophageal squamous cell carcinoma.Semantic proximity Read ↗

Prognostic value of the PIK3CA, AKT, and PTEN mutations in oral squamous cell carcinoma: literature reviewSemantic proximity Read ↗

Genetic alterations of the PIK3CA oncogene in human oral squamous cell carcinoma in an Indian population.Semantic proximity Read ↗

Mutational status of PIK3ca oncogene in oral cancer-In the new age of PI3K inhibitors.Semantic proximity Read ↗

PIK3CA gene mutations in breast carcinoma in Malaysian patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.