Article
The discovery of genes implicated in myocardial infarction.
Journal of thrombosis and haemostasis : JTH - 1 Jul 2009
Ouwehand W H
Abstract excerpt
The era of Genome-Wide Association Studies (GWAS) commenced in 2007 with the study of the Wellcome Trust Case Control Consortium (WTCCC) which for the first time ever showed that risk loci can be identified by scanning the complete genome for sequence variation in large numbers of cases of disease and healthy controls. We and others have expanded on this effort and successfully identified the first 11 risk loci...
Topics
- Coronary Artery Disease
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Myocardial Infarction
- Quantitative Trait Loci
