Genetics of myocardial infarction: a progress report

Abstract excerpt

A small region on chromosome 9p21.3, discovered in parallel by three groups in the year 2007, is typical of the new understanding of the genetic basis of myocardial infarction (MI). The finding emerged from the application of novel high-throughput genome-wide approaches, the risk-associated allele is frequent, acts independently of traditional risk factors, and confers a modest yet highly reproducible hazard....

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