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Article

Systematic manipulation of glutathione metabolism in Escherichia coli for improved glutathione production.

Microbial cell factories - 16 Feb 2016

Zhang Jing, Quan Cong, Wang Cheng, Wu Hui, Li Zhimin, Ye Qin

Abstract excerpt

BACKGROUND: L-glutathione (GSH) is a non-protein thiol compound with important biological properties and is widely used in pharmaceutical, food, cosmetic and health products. The cellular GSH is determined by the activity and characteristic of GSH-synthesizing enzymes, energy and precursor supply, and degradation of formed GSH. RESULTS: In this study, genes encoding enzymes related to the precursor amino acid...

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Identifiers

PMID: 26883423
DOI: 10.1186/s12934-016-0439-1
PMCID: PMC4754818

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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