Article
A Single Nucleotide Polymorphism in the FOXP3 Gene Associated with Behçet's Disease in an Iranian Population.
Clinical laboratory - 1 Jan 2015
Hosseini Arezoo, Shanehbandi Dariush, Estiar Mehrdad Asghari, Gholizadeh Saber, Khabbazi Alireza, Khodadadi Hamidreza, Sakhinia Ebrahim, Babaloo Zohreh
Abstract excerpt
UNLABELLED: Background: Behçet's Disease (BD) is a rare autoimmune disease that involves the dysfunction of regulatory T cells. FOXP3 is a key transcription factor in the development and function of T(reg) cells. Recent studies have shown SNPs in the FOXP3 contribute to the susceptibility to some autoimmune disorders. METHODS: To clarify the association between the FOXP3 gene and the risk of BD, 50 patients...
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