Article
Association of genetic variations in FoxP3 gene with Graves' disease in a Southwest Chinese Han population.
Immunity, inflammation and disease - 1 Oct 2023
Tan Guiqin, Zheng Guangbing, Li Jiang, Zhu Yingping, Liang Zhongzhi, Li Hua, Yu Hongsong, Wang Xin
Abstract excerpt
BACKGROUND: Graves' disease (GD) is a T cell-mediated organ-specific autoimmune disease. Forkhead box P3 (FoxP3) is an excellent marker for the induction and development of regulatory T cells (Tregs). Recent studies showed that single-nucleotide polymorphisms (SNPs) in the FoxP3 gene were associated with the increased susceptibility to several autoimmune diseases. In the present study, we investigated the...
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