Article
Contribution of DNA Double-strand Break Repair Gene XRCC3 Genotypes to Triple-negative Breast Cancer Risk.
Cancer genomics & proteomics - 1 Jan 2000
Su Chen-Hsien, Chang Wen-Shin, Hu Pei-Shin, Hsiao Chieh-Lun, Ji Hong-Xue, Liao Cheng-Hsi, Yueh Te-Cheng, Chuang Chin-Liang, Tsai Chia-Wen, Hsu Chin-Mu, Lane Hsien-Yuan, Bau Da-Tian
Abstract excerpt
AIM: The DNA-repair gene X-ray repair cross-complementing group 3 (XRCC3) is important in DNA double-strand break repair and plays a critical part in initiation of carcinogenesis. Triple-negative breast cancer (TNBC) is the most difficult breast cancer subtype with no existing gene-targeting drugs and little knowledge on its genetic etiology. This study aimed to investigate the contribution of the XRCC3 genotype...
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