Article
Single nucleotide polymorphism (SNP) Thr241Met in the XRCC3 gene and breast cancer risk in Polish women.
Polish journal of pathology : official journal of the Polish Society of Pathologists - 1 Jun 2012
Romanowicz-Makowska Hanna, Bryś Magdalena, Forma Ewa, Maciejczyk Rafał, Połać Ireneusz, Samulak Dariusz, Michalska Magdalena, Smolarz Beata
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) in DNA repair genes may be associated with differences in the repair efficiency of DNA damage and may influence an individual's risk of cancer. The XRCC3 protein plays a critical role in Homologous Recombination Repair (HRR) accounting for repair of DNA double-strand breaks (DSB). AIM: The aim of the present study was to evaluate associations between the risk of...
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