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Article

DNA repair gene XRCC3 polymorphisms and cancer risk: a meta-analysis of 48 case-control studies.

European journal of human genetics : EJHG - 1 Oct 2006

Han Shizhong, Zhang Hong-Tao, Wang Zhentian, Xie Yi, Tang Rong, Mao Yumin, Li Yao

Abstract excerpt

The X-ray repair cross-complementing group 3 (XRCC3) is a highly suspected candidate gene for cancer susceptibility. However, association studies on the XRCC3 polymorphisms (4541A>G, Thr(241)Met, 17893A>G) in cancer have shown conflicting results. Therefore, we performed a meta-analysis to better assess the purported associations. Forty eight eligible case-control studies including 24,975 cancer patients and 34,...

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Identifiers

PMID: 16791138
DOI: 10.1038/sj.ejhg.5201681

Genes

XRCC3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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