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Article

The Effects of Leptin Replacement on Neural Plasticity.

Neural plasticity - 1 Jan 2016

Paz-Filho Gilberto J

Abstract excerpt

Leptin, an adipokine synthesized and secreted mainly by the adipose tissue, has multiple effects on the regulation of food intake, energy expenditure, and metabolism. Its recently-approved analogue, metreleptin, has been evaluated in clinical trials for the treatment of patients with leptin deficiency due to mutations in the leptin gene, lipodystrophy syndromes, and hypothalamic amenorrhea. In such patients,...

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Identifiers

PMID: 26881138
DOI: 10.1155/2016/8528934
PMCID: PMC4735938

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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